Förfarande för framställning av kirala ämnen som rena optiska isomerer

摘要

A process for producing chiral compounds of high optical purity wherein enzymes catalyse a reaction between chiral and non-chiral starting materials in supercritical carbon dioxide so that principally only one of the optically active isomers of the chiral starting material reacts, and produces a new chiral compound which has higher optical purity than the starting material. By using supercritical carbon dioxide as the reaction medium the problems and risks of handling large amounts of organic solvents can be avoided.