发明名称 |
RECEPTOR INFECTION ASSAY |
摘要 |
The presente invention relates to improvements in a bioassay useful for identifying materials that function as ligands for a hormone or hormone-like receptor protein measured by means of induction of reporter DNA driven by a promoter of a hormone response element. The improvement comprises producing a cell operatively harboring DNA encoding reporter gene and receptor gene by coinfection of a mammalian cell with a viral expression vector. The expedient of this invention permits commercial realization and exploitation of the bioassay system. |
申请公布号 |
WO9106677(A1) |
申请公布日期 |
1991.05.16 |
申请号 |
WO1990US06129 |
申请日期 |
1990.10.23 |
申请人 |
THE SALK INSTITUTE FOR BIOLOGICAL STUDIES |
发明人 |
WEINBERGER, CARRY, ALAN |
分类号 |
C12N5/10;C12N15/09;C12P21/00;C12Q1/02;C12Q1/66;C12Q1/68;C12R1/91 |
主分类号 |
C12N5/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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