MUCOADHESIVE CARRIER FOR DELIVERY OF THERAPEUTICAL AGENT

摘要

A mucoadhesive carrier suitable for a therapeutic agent is disclosed. This carrier allows controlled release of the therapeutic agent via mucosal tissue. The mucoadhesive carrier comprises a monolithic polymer matrix (12) that is anhydrous but hydratable, and amorphous fumed silica. The silica enhances the mucoadhesive properties of the carrier. An optional water-insoluble barrier film or layer (14) can be secured to the polymer matrix (12) to provide a non-adhering face.