发明名称 4-Amidinochroman derivatives, process of production and pharmaceutical compositions containing them
摘要 The present invention relates to 4-amidinochroman derivatives of formula <IMAGE> in which: . A + B = either -CH=CH-CH=X1, with X1 = N or CH, or -(CH2)n-X2, with X2 = NH or CH2 and n = 2 or 3 . X = N or C-Z . Z = H, Cl, Br, F, CN, NO2, CH3CO or CF3CO . R1 = H, CN or NO2 . R2 = H; R3 = OH or R2 and R3 together form a bond. Another subject of the invention is a process for the preparation of the said derivatives and pharmaceutical compositions containing them. The said derivatives have antihypertensive and antiarrhythmic activities.
申请公布号 FR2654103(A1) 申请公布日期 1991.05.10
申请号 FR19890014518 申请日期 1989.11.06
申请人 SANOFI 发明人 GARCIA GEORGES;GAUTIER PATRICK;NISATO DINO;ROUX RICHARD
分类号 C07D405/04;C07D491/04 主分类号 C07D405/04
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