| 摘要 |
2068427 9107168 PCTABS00005 A method of enhancing in vivo melanin production is disclosed. The method comprises topically applying an effective amount of riboflavin, riboflavin phosphate or mixtures thereof to the surface of the skin. Also disclosed is a composition for enhancing in vivo melanin production. The composition comprises an effective amount of riboflavin, riboflavin phosphate or mixtures thereof. The composition can contain at least one other ingredient selected from the group consisting of: Protein Kinase C Activators, DOPA phosphates, sunscreening agents, emollients, emulsifiers, solvents for sunscreening agents, waxes, thickeners, film formers, humectants, antioxidants, perservatives, surfactants, perfumes, biological additives, buffering agents, chelating agents, emulsion stabilizers, opacifying agents, pH adjusters, propellants and coloring agents. The Protein Kinase C Activators in the methods and compositions of this invention can be selected from the group consisting of: diacylglycerols, triacylglycerols, lipopolysaccharides, unsaturated free fatty acids, short chain saturated free fatty acids, glycerolphospholipids, enzymes which hydrolyze glycophospholipids to diacylglycerols, and bryostatins.
|
