摘要 |
NEW MATERIAL:A compound shown by formula I [R<1> to R<3> are each -COOR<4>, -COOR<5> or -COOR<6> (R<4> to R<6> are H, lower alkyl, etc.); W is -OH; X, Y and Z are H or -OH; broken line is existence of double bond]. EXAMPLE:A compound shown by formula II. USE:A phospholipase A2 inhibitor. PREPARATION:A fungus [e.g. Circinotrichum falcatisporum RF-641 (FERM P-275A)] belonging to the genus Circinotrichum, capable of producing a compound shown by formula I, is cultured and the compound shown by formula I is collected from the culture solution. |