发明名称 PHOSPHOLIPASE A2 INHIBITOR
摘要 NEW MATERIAL:A compound shown by formula I [R<1> to R<3> are each -COOR<4>, -COOR<5> or -COOR<6> (R<4> to R<6> are H, lower alkyl, etc.); W is -OH; X, Y and Z are H or -OH; broken line is existence of double bond]. EXAMPLE:A compound shown by formula II. USE:A phospholipase A2 inhibitor. PREPARATION:A fungus [e.g. Circinotrichum falcatisporum RF-641 (FERM P-275A)] belonging to the genus Circinotrichum, capable of producing a compound shown by formula I, is cultured and the compound shown by formula I is collected from the culture solution.
申请公布号 JPH03108490(A) 申请公布日期 1991.05.08
申请号 JP19900148007 申请日期 1990.06.06
申请人 SHIONOGI & CO LTD 发明人 YOSHIDA TADASHI;ITAZAKI HIROSHI;ARITA HITOSHI;KAWAMURA YOSHIMI;MATSUMOTO KOICHI
分类号 C12P7/44;A61K31/19;A61K31/215;A61K31/365;A61P7/02;A61P43/00;C07C59/245;C07C59/42;C07C69/675;C07C69/732;C07D307/33;C07D493/10;C12N9/99;C12P7/42;C12P7/64;C12P17/02;C12P17/04;C12P17/18;C12R1/645 主分类号 C12P7/44
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