发明名称 Anticancer drug - antibody conjugates and method for preparing same
摘要 A drug-protein conjugate of the general formula (I): <IMAGE> (I) where the moiety A-NH- is the condensation product of an anticancer antibiotic having a free amino group, n is 0, 1 or 2, m is 0, 1, 2 or 3, the moiety -NHAB is the condensation product of a protein having a free amino group and the moiety <IMAGE> is the condensation product of an amino acid of the formula HOOC-AA-NH2.
申请公布号 US5013547(A) 申请公布日期 1991.05.07
申请号 US19890307644 申请日期 1989.02.07
申请人 ERBAMONT, INC. 发明人 SWEET, FREDERICK;ROSIK, LEONARD O.
分类号 A61K47/48 主分类号 A61K47/48
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