Sustained-release preparation of basic medical agent hydrochloride.

摘要

A preparation obtained by coating granules containing both a basic medical agent hydrochloride (e.g. arotinolol hydrochloride) and a polyanion the particles of which are present in the form of a discontinuous layer, with a film containing a slightly water-soluble substance, can release the agent at a controlled rate independently of physiological conditions in the gastrointestinal tract of a patient to whom the preparation has been administered orally.