NEUE BICYCLO-IMIDAZOLE, VERFAHREN ZU IHRER HERSTELLUNG UND DIESE VERBINDUNGEN ENTHALTENDE ARZNEIMITTEL

摘要

The invention relates to new bicyclo-imidazoles of formula (I), where R<1> is a hydrogen atom, a C1-C6 alkyl, C2-C6 alkenyl or C3-C7 cycloalkyl group, R<2> is a C1-C6 alkyl, C2-C6 alkenyl or cyanogen group, a carbonyl group substituted by a hydroxy, C1-C6 alkyl, C1-C6 alkoxy, amino, C1-C6 alkylamino, di-C1-C6 alkylamino or hydrazino group, or R<1> and R<2> together stand for a C2-C6 alkylidene or C3-C6 cycloalkylidene group, or R<1> and R<2>, together with the carbon atom to which they are linked, form a C3-C7 spirocycle, n is equal to 0 or 1, R<3> is a hydrogen atom, a C1-C8 alkyl, C2-C6 alkenyl, C2-C6 alkinyl, C3-C7 cycloalkyl, benzyl, carboxy C1-C6 alkyl, C1-C6 alkoxycarbonyl-C1-C6 alkyl or dimethyloxophosphinylmethyl group, R<4> is a pyridinyl or substituted phenyl ring. The invention also relates to a process for producing these compounds and drugs containing them. The compounds of the invention prevent clumping of both erythrocytes and thrombocytes.