发明名称 2 STAGE DRUG DELIVERY DEVICE
摘要 <p>The invention provides a dosage form (10) for delivering the beneficial drugs (17) pseudoephedrine and brompheniramine to an environment of use, the dosage form comprising: a) a semi-permeable wall (12), permeable to the passage of fluid present in the environment of use but substantially impermeable to the passage of the drug, which wall surrounds and defines, b) a compartment 16 containing a dosage amount of a beneficial agent (17) for delivery to the environment of use at a controlled rate, and c) at least one passageway (14) in the wall (12) for connecting the interior of the compartment with the environment of use, characterized by a lamina (13) comprising a beneficial drug disposed upon the exterior of the semi-permeable wall (12), said lamina being adapted for transfer of a beneficial agent to the environment of use for immediate therapeutic effect.</p>
申请公布号 EP0237159(B1) 申请公布日期 1991.05.02
申请号 EP19870300694 申请日期 1987.01.27
申请人 ALZA CORPORATION 发明人 HAMEL, LARRY;WONG, PATRICK S.-L.;LANDRAU, FELIX A.;GUITTARD, GEORGE V.
分类号 A61K31/44;A61K9/00;A61K9/02;A61K9/22;A61K31/135;A61K31/137;A61P43/00 主分类号 A61K31/44
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