发明名称 BIOAVAILABILITY OF PHARMACEUTICAL ACTIVE COMPOUNDS WITH PEPTIDE LINKAGES
摘要 Pharmaceutical active compounds which contain peptide linkages and are therefore sensitive are protected from degradation, during passage through the stomach and intestines, by micronization. This improves the absorption and bioavailability. In the micronization the active compounds are extremely finely divided, and each particle is provided with a colloid protective envelope.
申请公布号 CA2028665(A1) 申请公布日期 1991.04.29
申请号 CA19902028665 申请日期 1990.10.26
申请人 HORN, DIETER;END, LUTZ;SPENGLER, REINHARD;KRAUSE, HANS-JUERGEN;ELZNER, JUERGEN 发明人 HORN, DIETER;END, LUTZ;SPENGLER, REINHARD;KRAUSE, HANS-JUERGEN;ELZNER, JUERGEN
分类号 A61K9/14;A61K9/50;A61K38/00;C07K1/00;C07K14/52;C07K14/555;C07K14/57;C07K14/705;C07K14/81;(IPC1-7):A61K9/14 主分类号 A61K9/14
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