| 摘要 |
This invention relates to local epidural or intraspinal use of compounds of the formula: <CHEM> where X is H or CH3 and R1 and R2, which can be the same or different, are each H or CH3 and their stereoisomers and their non-toxic, pharmaceutically acceptable salts. Especially useful are the compounds known under the generic names medetomidine ((+/-)-4-[1-(2,3-dimethylphenyl)ethyl]-1H-imidazole), dexmedetomidine (+)-4-[1-(2,3-dimethylphenyl)ethyl]-1H-imidazole and detomidine 4-(2,3-dimethylbenzyl)-1H-imidazole. |
