发明名称 RECOMBINANT FUSION PROTEINS FOR ALTERING HORMONE SECRETION
摘要 A recombinant fusion protein, resulting from the expression of two genes regulated by a single promoter, having the effect of altering hormone secretion when administered in a therapeutically effective dose. One gene codes for the production of a highly antigenic, hydrophilic protein, such as hepatitis B surface antigen, and the other gene codes for a peptide which alone is not substantially antigenic, such as luteinizing hormone releasing hormone.
申请公布号 ZA8906628(B) 申请公布日期 1991.04.24
申请号 ZA19890006628 申请日期 1989.08.30
申请人 APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. 发明人 SCOTT C. CHAPPEL;NOREEN P. NUGENT
分类号 C12N15/09;A61K39/29;A61K39/395;A61K39/42;A61P5/00;C07K7/23;C07K14/00;C07K14/02;C07K14/10;C07K14/18;C07K14/575;C07K14/59;C07K14/705;C07K19/00;C12N15/62;C12P21/00;C12R1/91 主分类号 C12N15/09
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