发明名称 |
RECOMBINANT FUSION PROTEINS FOR ALTERING HORMONE SECRETION |
摘要 |
A recombinant fusion protein, resulting from the expression of two genes regulated by a single promoter, having the effect of altering hormone secretion when administered in a therapeutically effective dose. One gene codes for the production of a highly antigenic, hydrophilic protein, such as hepatitis B surface antigen, and the other gene codes for a peptide which alone is not substantially antigenic, such as luteinizing hormone releasing hormone. |
申请公布号 |
ZA8906628(B) |
申请公布日期 |
1991.04.24 |
申请号 |
ZA19890006628 |
申请日期 |
1989.08.30 |
申请人 |
APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. |
发明人 |
SCOTT C. CHAPPEL;NOREEN P. NUGENT |
分类号 |
C12N15/09;A61K39/29;A61K39/395;A61K39/42;A61P5/00;C07K7/23;C07K14/00;C07K14/02;C07K14/10;C07K14/18;C07K14/575;C07K14/59;C07K14/705;C07K19/00;C12N15/62;C12P21/00;C12R1/91 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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