| 发明名称 |
HUMAN NERVE GROWTH FACTOR |
| 摘要 |
A method for the construction of recombinant DNA molecules capable of producing biologically active human nerve growth factor (hNGF) in insect cells is disclosed. Expression of the mature protein is achieved using the baculovirus expression system. The biologically active hNGF so produced is potentially of value in the treatment of patients suffering from Alzheimer's Disease and other neurological disorders. |
| 申请公布号 |
ZA8905661(B) |
申请公布日期 |
1991.04.24 |
| 申请号 |
ZA19890005661 |
申请日期 |
1989.07.25 |
| 申请人 |
SYNTEX (U.S.A.) INC. |
发明人 |
HARDY WAI-HONG CHAN;JIM WAYNE BARNETT;PRESTON ALBERT BAECKER;HELA BURTSZTYN-PETTEGREW;BINH TRONG NGUYEN;CAROL WARD |
| 分类号 |
C12N15/09;A61K38/00;A61K38/22;A61K38/27;A61P25/28;C07K1/20;C07K1/22;C07K14/48;C07K14/52;C12N5/10;C12N15/16;C12N15/866;C12P21/02;C12R1/91 |
主分类号 |
C12N15/09 |
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