摘要 |
Shionogi /A Co., Ltd. Carbamoyloxymethylalkylcarbapenem compounds Inventor: Shoichiro Uyeo - A highly efficient antibacterial (1,5R,6S)-6-¢(1R)-1 hydroxyethyl!-2-optionally alkylated carbamoyloxymethyl-1-alkyl-1-carba-pen-2-em-3-carboxylic acid and its derivative represented by formula 1 and its preparation are given: (I) (wherein, R1 is hydrogen or a hydroxy-protecting group; R2 is lower alkyl; R3 is hydrogen or lower alkyl; and R4 is hydrogen or a salt- or ester-forming group). |