ANTI-HYPERTENSIVE COMPOSITIONS OF SECONDARY AMINE-NITRIC OXIDE ADDUCTS AND USE THEREOF

摘要

This invention concerns anti-hypertensive compositions and a method of lowering blood pressure in mammals. The active component of the compositions is a compound of the formula: I wherein R1 and R2 are independently chosen from straight chain and branched chain C1-C12 alkyl groups and benzyl, with the proviso that no branch occur on the alpha carbon atom of the alkyl groups; or R1 and R2 together with the nitrogen atom they are bonded to form a pyrrolidino, piperidino, piperazino or morpholino group, M+is a pharmaceutically acceptable cation, wherein X is the valence of the cation.