发明名称 |
Human monoclonal antibodies to cell surface antigens of melanoma |
摘要 |
This invention provides a monoclonal antibody, produced by the hybridoma cell line designated GXM1, which specifically binds to a human class 1tumor antigen. This invention also provides a human monoclonal antibody, produced by a hybridoma cell line designated HJM1, which specifically binds to each of the ganglioside antigens GD2, GD3, GM3 and GD1b. This invention further provides a human monoclonal antibody, produced by a hybridoma cell line designated FCM1, which specifically binds to the ganglioside antigens GM3 and GD1a. Finally, this invention provides a human monoclonal antibody, produced by a hybridoma cell line designated DSM1, which specifically binds to a human class 2 tumor protein antigen.
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申请公布号 |
US5006470(A) |
申请公布日期 |
1991.04.09 |
申请号 |
US19870039479 |
申请日期 |
1987.04.16 |
申请人 |
SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH |
发明人 |
YAMAGUCHI, HIROSHI;FURUKAWA, KOICHI;LIVINGSTON, PHILIP O.;LLOYD, KENNETH O.;OETTGEN, HERBERT F.;OLD, LLOYD J.;FORTUNATO, SHEILA R. |
分类号 |
A61K38/00;A61K47/48;C07K16/30 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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