发明名称 NEW ANTI-BACTERIAL AND ANTI-PLAQUE COMPOUND FOR ORAL CAVITY CONTAINING STYRENE PHDSPHONONIC ACID COPOLYMER
摘要 NEW MATERIAL: A polymer selected from aβ-styrenephosphonic acid polymer, anα-styrene phosphonic acid polymer and copolymers between any of the styrenephosphonic acids and one or more other ethylenic unsaturated polymerizable monomers. EXAMPLE: A poly(α-styrenephosphonic acid). USE: An oral cavity composition comprises a polymer having 2,000-10,000 molecular weight, which is substantially a water-insoluble nonionic antimicrobial agent, improves the delivery of the agent to the surface of the oral cavity and protection of the surface of the oral cavity and reduces crisis of gingivitis. PROCESS: A monomer or a monomer mixture is polymerized in a solvent in the presence of a free radical initiator under heating. The prepared granular polymer is mixed with water and the solution is adjusted to pH8-10 by an aqueous solution of NaOH. The solution is dialyzed against water to give the purified polymer as the new substance.
申请公布号 JPH0383910(A) 申请公布日期 1991.04.09
申请号 JP19900000213 申请日期 1990.01.04
申请人 COLGATE PALMOLIVE CO 发明人 ABUTARU GATSUFUAA;NURAN NABI;JIYON AFURITSUTO;OORAMU SUTORINGAA;MAIKERU PURENSHIPU
分类号 A61K8/00;A61K8/34;A61K8/42;A61K8/81;A61P31/02;A61Q11/00;C08F2/38;C08F6/10;C08F30/02 主分类号 A61K8/00
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