| 摘要 |
PCT No. PCT/DK90/00201 Sec. 371 Date Jan. 29, 1992 Sec. 102(e) Date Jan. 29, 1992 PCT Filed Aug. 9, 1990 PCT Pub. No. WO91/03466 PCT Pub. Date Mar. 21, 1991. <IMAGE> (I) The present invention relates to hitherto unknown compounds of formula, in which m and n stand for an integer from 0-5, p stands for 0 or 1, and q stands for an integer from 0-4, R1 and R2 are the same or different and stand for hydrogen, halogen, nitro, amino, alkyl or alkoxy; R3 is hydroxy, hydrogen, straight or branched, saturated or unsaturated C1-C6 alkyl; R5 stands for an acidic group, e.g. carboxy, 1-H tetrazolyl, a sulphonic acid group, a sulfamyl group, a sulphinic acid group, or a hydroxamic acid group; R4 and R6 are the same or different and stand for hydrogen, straight or branched, saturated or unsaturated, unsubstituted or substituted C1-C6 alkyl groups or unsubstituted or substituted aralkyl groups. R7 has the same meaning as R5 or represents a hydrogen, straight or branched, saturated or unsaturated, unsubstituted or substituted C1-C6-alkyl group. The present compounds are of value in the human and veterinary practice as lipoxygenase inhibitors and/or leukotriene antagonists. |
