发明名称 NOVEL HYDROLYTIC ENZYME INHIBITORS AND SUBSTRATES AND ASSAYS, METHODS AND KITS EMBODYING SAME
摘要 The present invention provides compounds that function as hydrolytic enzyme inhibitors (inactivators) and substrates. These compounds are useful in assays to detect and measure levels of hydrolytic enzyme activity and are more particularly useful in treatment regimens for various disease states and conditions implicating the underlying specific hydrolytic enzyme. Examples of hydrolytic enzymes include, but are not limited to, phospholipases, lipases, esterases, proteases, etc.
申请公布号 AU6353090(A) 申请公布日期 1991.04.08
申请号 AU19900063530 申请日期 1990.08.17
申请人 THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 发明人 EDWARD A. DENNIS;WILLIAM N. WASHBURN
分类号 A61K31/215;A61K31/00;A61K31/22;A61K31/235;A61K31/66;A61K38/55;A61P29/00;C07C69/40;C07C69/708;C07C69/74;C07C69/75;C07C69/753;C07C69/76;C07C69/80;C07C237/22;C07C323/22;C07C327/20;C07C327/58;C07D311/16;C07F9/10;C12Q1/34;C12Q1/44 主分类号 A61K31/215
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