发明名称 |
NOVEL HYDROLYTIC ENZYME INHIBITORS AND SUBSTRATES AND ASSAYS, METHODS AND KITS EMBODYING SAME |
摘要 |
The present invention provides compounds that function as hydrolytic enzyme inhibitors (inactivators) and substrates. These compounds are useful in assays to detect and measure levels of hydrolytic enzyme activity and are more particularly useful in treatment regimens for various disease states and conditions implicating the underlying specific hydrolytic enzyme. Examples of hydrolytic enzymes include, but are not limited to, phospholipases, lipases, esterases, proteases, etc. |
申请公布号 |
AU6353090(A) |
申请公布日期 |
1991.04.08 |
申请号 |
AU19900063530 |
申请日期 |
1990.08.17 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
EDWARD A. DENNIS;WILLIAM N. WASHBURN |
分类号 |
A61K31/215;A61K31/00;A61K31/22;A61K31/235;A61K31/66;A61K38/55;A61P29/00;C07C69/40;C07C69/708;C07C69/74;C07C69/75;C07C69/753;C07C69/76;C07C69/80;C07C237/22;C07C323/22;C07C327/20;C07C327/58;C07D311/16;C07F9/10;C12Q1/34;C12Q1/44 |
主分类号 |
A61K31/215 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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