发明名称 |
TOCOTRIENOLS IN THE TREATMENT OF HYPERCHOLESTEROLEMIA, HYPERLIPIDEMIA AND THROMBOEMBOLIC DISORDERS |
摘要 |
This invention relates to the use of tocotrienol, gamma-tocotrienol and delta-tocotrienol in reducing hypercholesterolemia, hyperlipidemia and thromboembolic disorders in mammals. The isolation of these tocotrienols from natural sources and their chemical synthesis is disclosed. The present invention also relates to prodrugs and pharmaceutical compositions of gamma-tocotrienol, delta-tocotrienol and tocotrienol and uses thereof.
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申请公布号 |
CA2026713(A1) |
申请公布日期 |
1991.04.05 |
申请号 |
CA19902026713 |
申请日期 |
1990.10.02 |
申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
WRIGHT, JOHN J.;PEARCE, BRADLEY C.;PARKER, REX A.;QURESHI, ASAF A. |
分类号 |
A61K31/352;A61K31/355;A61P3/06;A61P7/02;A61P43/00;C07D311/72;(IPC1-7):A61K31/35 |
主分类号 |
A61K31/352 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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