发明名称 |
CHELATE DERIVATIVE AS ATRIAL SODIUM DIURETIC FACTOR (ANF) |
摘要 |
Derivatives of synthetic fragments of mammalian atrial natriuretic factor (ANF) in which a chelate molecule is attached to the N-terminal of the peptide are described. The chelate component allows the facile labelling of these peptides with metallic isotopes such as Tc-99m, Ga-67, In-111 and others. These radioactive chelates are useful in determining the in vivo behavior and fate of derivatives of ANF. |
申请公布号 |
JPH0381295(A) |
申请公布日期 |
1991.04.05 |
申请号 |
JP19900155629 |
申请日期 |
1990.06.15 |
申请人 |
MERCK FROSST CANADA INC |
发明人 |
RICHIYAADO JIEE FURANAGAN;EFU PIITAA CHIYAARUSON |
分类号 |
G01N33/60;A61K38/22;A61K51/08;A61P3/00;A61P7/10;A61P9/12;C07K14/575;C07K14/58 |
主分类号 |
G01N33/60 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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