发明名称 |
Non-covalent antibody-anthracycline immunocomplexes |
摘要 |
A composition comprising a non-covalent immunocomplex of an anthracycline agent and an antibody selected to bind a target antigen and enhance the cytotoxicity of the anthracycline agent is disclosed. In accordance with the invention, the efficacy of an anthracycline as an anti-tumor agent for use in in vivo therapy is enhanced by administering to a patient a non-covalent immunocomplex provided herein.
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申请公布号 |
US5004606(A) |
申请公布日期 |
1991.04.02 |
申请号 |
US19860911269 |
申请日期 |
1986.09.24 |
申请人 |
HYBRITECH INCORPORATED |
发明人 |
FRINCKE, JAMES M.;BARTHOLOMEW, RICHARD M.;DILLMAN, ROBERT O. |
分类号 |
A61K47/48 |
主分类号 |
A61K47/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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