发明名称 Method and apparatus for enhanced drug permeation of skin
摘要 A method and apparatus for preparation of a selected area of skin to facilitate drug absorption comprises removal of the outermost layers of the skin by gentle abrasion or other means, measuring the change in electrical resistance or impedance of the skin as the outermost layers of the skin are removed, and stopping skin removal when a predetermined optimum skin resistance or impedance is achieved to facilitate drug absorption. The preferred electrical resistance or impedance meter is in contact with the skin under consideration by two separate but adjacent conductive poles and is purpose calibrated to signal when the skin resistance or impedance level is such that rapid absorption of a drug will occur.
申请公布号 US5003987(A) 申请公布日期 1991.04.02
申请号 US19880241354 申请日期 1988.09.08
申请人 GRINWALD, PAUL M. 发明人 GRINWALD, PAUL M.
分类号 A61B5/0402;A61B5/053 主分类号 A61B5/0402
代理机构 代理人
主权项
地址