摘要 |
Process for obtaining 1-aryloxy-3-nitroamino-2-propanols of formula I where: Ar represents a phenyl or naphthyl radical; R1 and R2, which may be the same or different, can occupy any substitution position relative to the aromatic nucleus and represent hydrogen or a straight or branched alkyl chain of 1 to 4 carbon atoms; and R3 represents a straight or branched alkyl chain of 1 to 4 carbon atoms, based on the reaction of a 1-aryloxy-3- amino-2-propanol of formula <IMAGE> in which Ar, R1, R2 and R3 have the meanings indicated above, with a member of the group comprising thionyl nitrate chloride and n-nitro collidine tetrafluorate. These compounds are of pharmacological use, particularly for cardiovascular activity. <IMAGE>
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