发明名称 Process for obtaining enrofloxacin
摘要 Process for obtaining enrofloxacin having the chemical name 1-cyclopropyl-7-(4-ethyl-1-piperazinyl)-6-fluoro-1,4- dihydro-4-oxoquinolin-3-carboxylic acid of formula I, its addition salts with pharmaceutically acceptable acids and its hydrates, based on the reaction of 3-acetyl-1- cyclopropyl-7-chloro-6-fluoro-1,4-dihydro-4-oxoquinolein, of formula V, <IMAGE> with an excess of N-ethylpiperazine and subsequent oxidation of the reaction product. Enrofloxacin is a bactericidal agent of proven effectiveness in the veterinary field in the prevention and treatment of infectious diseases. <IMAGE>
申请公布号 ES2018414(A6) 申请公布日期 1991.04.01
申请号 ES19890003703 申请日期 1989.11.02
申请人 UNION QUIMICO FARMACEUTICA, S.A. 发明人 LOPEZ MOLINA ISIDRO;DOMINGO COTO ANTONIO;PALOMO COLL ALBERTO
分类号 A01N43/42;A01N43/60;A61K31/445;A61K31/495;C07D401/10;(IPC1-7):C07D401/10 主分类号 A01N43/42
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