| 摘要 |
A cardiac pacing lead or other stimulation lead carrying a drug compounded into a matrix, located within the distal portion of the lead. The drug is delivered to the tissue adjacent the distal end of the lead. In connection with the polymer matrix, the lead is provided with a penetrating electrode, which takes the form of a sharpened helix. The electrode is provided with a groove, running the length of the electrode and exposed to the matrix. In use, the drug elutes out of the matrix, through the groove in the electrode, and into the tissue to be stimulated. The drug may be an antiinflammatory agent, such as a glucocorticosteroid, to minimize the effects of implantation of the electrode into the tissue to be stimulated.
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