| 发明名称 |
AMINO ACID DERIVATIVES |
| 摘要 |
New amino acid derivatives of the formula I R1-CpH2p-(NH)q-CO-NH-CHR2-CO-Z-CmH2m-CHWR3-CO- NH-CHR3-CR4-(CHR5)n-CO-E-Q-Y I in which R1 to R5 p, q, Z, m, n, E, Q, W and Y have the meanings indicated in Patent Claim 1, and the salts thereof, inhibit the activity of human plasma renin.
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| 申请公布号 |
CA2025860(A1) |
申请公布日期 |
1991.03.23 |
| 申请号 |
CA19902025860 |
申请日期 |
1990.09.20 |
| 申请人 |
MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG |
发明人 |
JURASZYK, HORST;RADDATZ, PETER;SOMBROEK, JOHANNES;GANTE, JOACHIM;SCHMITGES CLAUS J.;MINCK, KLAUS-OTTO |
| 分类号 |
C07D295/04;A61K31/41;A61K31/44;A61K31/4402;A61K31/4406;A61K31/4409;A61K31/4412;A61K31/4418;A61K31/4427;A61K31/445;A61K31/4468;A61K31/495;A61K31/505;A61K38/00;A61P9/12;A61P43/00;C07C237/22;C07C271/22;C07C275/14;C07C275/16;C07C279/12;C07C281/06;C07C311/39;C07C323/59;C07C323/60;C07D211/36;C07D213/56;C07D233/54;C07D239/42;C07D241/20;C07D257/04;C07D257/06;C07D295/15;C07D401/12;C07K1/02;C07K1/113;C07K5/02;C07K5/06;C07K14/81;(IPC1-7):C07K5/00;A61K38/05;A61K38/06 |
主分类号 |
C07D295/04 |
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