| 摘要 |
<p>A hyperthermic treatment of lung cancer, by temporarily filling with a liquid medium (110) preselected pulmonary air passages (30') adjoining pulmonary tissues containing malignant cells (108), circulating exogenously or intracorporally, ultrasonically heated liquid medium (110) at from about 41 °C to about 50 °C through the liquid-filled pulmonary air passages (30, 30'), and thereafter removing the liquid medium (110). The liquid medium (110) may be a perfluorocarbon liquid or physiological saline solution. Suitable perfluorocarbon liquids are characterized by an average molecular weight in the range of from about 350 to about 560 for exogenously heated liquids, e.g. FC-84, FC-72, RM-82, FC-75, RM-101 and perfluorodecalin; or in the range of from about 400 to about 500 for intracorporally, ultrasonically heated liquids. Also, liquid infusion and isolation catheters (20), intracavitary ultrasound applicators (76, 130), and intercostal ultrasound applicators (66, 68) for the disclosed convection and/or ultrasound hyperthermia treatments of lung cancer.</p> |
