发明名称 METHOD FOR IMPROVING HUMAN MONOCLONAL ANTIBODY PRODUCTION
摘要 2066720 9104336 PCTABS00003 Human monoclonal antibodies are expressed by recombinant mammalian cells transformed with vectors containing genes encoding the heavy and light chains of the human monoclonal antibodies. The genes were isolated from a genomic library constructed from a human/human or human/murine hybridoma which produces the antibodies.
申请公布号 CA2066720(A1) 申请公布日期 1991.03.20
申请号 CA19902066720 申请日期 1990.09.19
申请人 CENTOCOR, INC. 发明人 KNIGHT, DAVID M.;GHRAYEB, JOHN
分类号 A61K39/395;A61K38/00;C07K16/00;C07K16/12;C12P21/08;(IPC1-7):C12P21/08;C12N5/10;C12N5/18 主分类号 A61K39/395
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