摘要 |
<p>3-Substituted vinyl cephalosporin derivatives represented by the following formula: <CHEM> wherein R<1> represents a hydroxyl or lower alkoxyl group, X represents a nitrogen atom or a group represented by the formula -CH=, R<2> represents a carboxyl group or a carboxyl group protected with a protecting group, and R<3> is as defined herein, and pharmaoeutically acceptable salts thereof are potent antibacterial agents. Processes for their preparation, intermediates in such processes, and antibacterial compositions containing them as active ingredients are also described.</p> |