发明名称 NOVEL ANTIBIOTIC SUBSTANCE MK3990 AND ITS PRODUCTION
摘要 NEW MATERIAL:A compound having the following physical and chemical properties. Appearance, colorless plate crystal; melting point, 173-175 deg.C; molecular formula, C48H60N8O10; molecular weight, 908 (SI-MS, m/z 909 MH<+>); elemental analysis (%), C 61.24, H 6.85, N 11.89; specific rotation, [a]=+70.4 deg.C (C=0.3, MeOH); solubility, soluble in methanol, ethanol, acetone, ethyl acetate, etc., and scarcely soluble in water, chloroform, etc.; color reaction, positive to 10% sulfuric acid, molybdic acid, potassium permanganate, etc., and negative to ninhydrin reagent, etc.; neutral; etc. USE:Antibacterial agent against Gram-positive bacteria and anaerobic bacteria. PREPARATION:A microbial strain belonging to genus Basidiobolus [e. g. Basidiobolus meristosporus M-1540 (FERM P-10831)] is cultured at 20-27 deg.C for 3-10 days by submerged cultivation.
申请公布号 JPH0363288(A) 申请公布日期 1991.03.19
申请号 JP19890198060 申请日期 1989.08.01
申请人 MEIJI SEIKA KAISHA LTD;MITSUBISHI KASEI CORP 发明人 YOSHIDA SHIGEMI;MIYAJI SHINJI;SEZAKI MASAJI;MIKAWA TAKASHI;CHIBA NORIKO;OGISHI HARUYUKI
分类号 C12P21/02;A61K38/00;A61P31/04;C07G11/00;C07K7/06;C07K14/195;C07K14/41;C12R1/645 主分类号 C12P21/02
代理机构 代理人
主权项
地址