| 摘要 |
PURPOSE:To provide a preparation effective for Ca dysbolisms such as hypercalcemia, hypercalciuria and osteoporosis, comprising 24,25- dihydroxycholecalciferol and sesame oil. CONSTITUTION:0.00001-1.0wt.% (preferably 0.001-0.1) of 24,25- dihydroxycholecalciferol [24,25-(OH)2-D3] is dissolved in sesame oil to provide the subject preparation. An oil squeezed from sesame all can be used as the sesame oil but an oil having a peroxide value of 0-2.1me/kg (preferably 0-1.0me/kg) is especially preferable. The 24,25-(OH)2-D3 includes 24R,25- and 24S, 25- isomers and may be dissolved in the sesame oil after dissolved in an organic solvent. The preparation may be compounded if necessary with a flavor, aromatic agent, thickener, preservative, etc. |
