| 发明名称 |
LIPOXYGENASE INHIBITORS |
| 摘要 |
TITLE OF THE INVENTION LIPOXYGENASE INHIBITORS Compounds of the Formula I: <IMG> I and pharmaceutically acceptable salts thereof are inhibitors of leukotriene biosynthesis. These compounds inhibit the mammalian 5-lipoxygenase enzyme, thus preventing the metabolism of arachidonic acid to the leukotrienes. These compounds are thus useful in the treatment of asthma, allergic disorders, inflammation, skin diseases and certain cardiovascular disorders.
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| 申请公布号 |
CA1281329(C) |
申请公布日期 |
1991.03.12 |
| 申请号 |
CA19840466740 |
申请日期 |
1984.10.31 |
| 申请人 |
ATKINSON, JOSEPH G.;GUINDON, YVAN;LAU, CHEUK K. |
发明人 |
ATKINSON, JOSEPH G.;GUINDON, YVAN;LAU, CHEUK K. |
| 分类号 |
A61K31/34;A61K31/343;A61K31/35;A61K31/357;A61K31/38;A61K31/381;A61K31/41;A61K31/44;A61K31/443;A61P9/08;A61P29/00;A61P43/00;C07D307/79;C07D307/80;C07D307/85;C07D307/86;C07D317/00;C07D333/60;C07D333/70;C07D405/06;C07D405/12;C07D407/12;C07D493/04;C07F5/02;(IPC1-7):C07D307/78;C07D405/02 |
主分类号 |
A61K31/34 |
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