| 发明名称 |
Aryl-substituted thiophene 3-ols, derivatives and analogs useful as lipoxgenase inhibitors |
| 摘要 |
Aryl substituted thiophenes 3-ols, its dihydro derivatives, 1-oxide and 1,1-dioxide analogs, as well as aryl substituted furans, are 5-lipoxygenase inhibitors useful in the treatment of inflammation and other leukotriene-mediated diseases.
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| 申请公布号 |
US4999436(A) |
申请公布日期 |
1991.03.12 |
| 申请号 |
US19890397325 |
申请日期 |
1989.08.22 |
| 申请人 |
MERCK & CO., INC. |
发明人 |
WITZEL, BRUCE E.;ALLISON, DEBRA L.;CALDWELL, CHARLES G.;RUPPRECHT, KATHLEEN |
| 分类号 |
C07D333/32;C07D333/50;C07D333/64;C07D333/78;C07D333/80;C07D409/04 |
主分类号 |
C07D333/32 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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