发明名称 Sulfonamide derivatives and drugs obtained therefrom
摘要 Sulfonamide derivatives of the formula I <IMAGE> I where R1 is a C1-C4-alkyl or phenyl group which may be substituted by halogen, trifluoromethyl or C1-C4-alkyl, R2 is hydrogen or C1-C4-alkyl, A is a group CHOR3+L, C=O, C=S or C=N-OR4, R3 is hydrogen, C1-C4-alkyl phenyl, benzyl or C1-C4-acyl, R4 is hydrogen or methyl, B may be methylene or ethylene in the m or p position or, of A is not carbonyl, may be methyleneoxy, the oxygen atom being bonded to the aromatic, and E is a carboxyl, phosphonic acid or sulfo radical, their physiologically acceptable salts, esters with C1-C4-alcohols or amides or the tetrazol-5-yl radical, their preparation and their use as drugs.
申请公布号 US4999345(A) 申请公布日期 1991.03.12
申请号 US19890357266 申请日期 1989.05.26
申请人 BASF AKTIENGESELLSCHAFT 发明人 SCHMIED, BERNHARD;LEHMANN, HAND D.;BALDINGER, VERENA;RUEBSAMEN, KLAUS
分类号 A61K31/18;A61K31/185;A61K31/19;A61K31/22;A61K31/41;A61K31/66;A61K31/675;A61P7/02;A61P9/10;A61P35/00;C07C311/03;C07C311/04;C07C311/05;C07C311/16;C07C311/17;C07C311/18;C07C311/19;C07D257/04;C07F9/09;C07F9/38;C07F9/6524 主分类号 A61K31/18
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