发明名称 |
Method for x and y spermatozoa separation |
摘要 |
A method for separating male and female determining spermatozoa includes the initial step of exposing freshly ejaculated spermatozoa in a substantially protein free diluent to an excess concentration of a monoclonal antibody directed against H-Y antigen that binds substantially exclusively with male determining spermatozoa. The method continues with the suspending of the exposed spermatozoa together with a conjugate of (1) an immunoglobulin G antibody that binds substantially exclusively to the monoclonal antibody and (2) an immunoabsorbant substrate in a substantially protein free diluent. This forms a conjugate/spermatozoa preparation. The method concludes with the recovering of the separated male and female determining spermatozoa.
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申请公布号 |
US4999283(A) |
申请公布日期 |
1991.03.12 |
申请号 |
US19890396738 |
申请日期 |
1989.08.18 |
申请人 |
UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION |
发明人 |
ZAVOS, PANAYIOTIS M.;DAWSON, KARL A. |
分类号 |
A01N1/02;A61K35/52;C12N5/08 |
主分类号 |
A01N1/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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