摘要 |
Recombinant retroviruses carrying a vector construct capable of preventing, inhibiting, stabilizing or reversing infectious, cancerous or auto-immune diseases are disclosed. More specifically, the recombinant retroviruses of the present invention are useful for (a) stimulating a specific immune response to an antigen or a pathogenic antigen; (b) inhibiting a function of a pathogenic agent, such as a virus; and (c) inhibiting the interaction of an agent with a host cell receptor. In addition, eucaryotic cells infected with, and pharmaceutical compositions containing such a recombinant retrovirus are disclosed. Various methods for producing recombinant retroviruses having unique characteristics, and methods for producing transgenic packaging animals or insects are also disclosed. |
申请人 |
VIAGENE, INC. |
发明人 |
GRUBER, HARRY, E.;JOLLY, DOUGLAS, J.;RESPESS, JAMES, G.;LAIKIND, PAUL, K.;CHANG, STEPHEN, M., W.;CHADA, SUNIL, D.;WARNER, JOHN, F.;BARBER, JACK, R.;ST. LOUIS, DANIEL, C. |