| 摘要 |
<p>A compound having the formula <IMAGE> wherein R1 represents an indanyl, indolyl, quinolyl or chromonyl group, the group of the formula <IMAGE> (in which R2 represents a halogen atom or a nitro group), or the group of the formula <IMAGE> (in which R3 represents a halogen atom, or an alkyl, nitro, cyano, acetamino, aminosulfonyl, benzoyl, phenoxy or trifluoromethyl group, R4 represents a hydrogen or halogen atom, or an alkyl group, and R5 represents a hydrogen or halogen atom, or an alkyl group), or a pharmaceutically acceptable salt thereof. The compound is obtained by reacting 4-guanidinomethylcyclohexanecarboxylic acid or a reactive derivative thereof with a compound of the formula R1-OH wherein R1 is the same as defined above, or a reactive derivative thereof.</p> |
| 申请人 |
NIPPON CHEMIPHAR CO. LTD., TOKIO/TOKYO, JP |
发明人 |
MURAMATSU, MUTSUMI;SATOH, TOSHIO, TOKUSHIMA, JP;SEKINE, HIROYASU, KISAI, SAITAMA, JP;TENDO, ATSUSHI, TOKIO/TOKYO, JP;KIKAWA, YOSHIO, MISATO, SAITAMA, JP;KONDO, KANAME, TOKIO/TOKYO, JP |
