摘要 |
Antiviral compositions useful for inhibition of the cytopathic effects of the human immunodeficiency virus (HIV), which is implicated as a causative agent of AIDS (Acquired Immune Deficiency Syndrome), include a new class of HIV-inhibitory compounds, the sulfonic acid-containing glycolipids. The pure compounds were active against HIV in cultured human lymphoblastoid CEM, MT-2, LVD-7 and C3-44 cell lines as indicated by the tetrazolium assay, as well as by correlative p24 viral protein and syncytia formation assays. |
申请人 |
THE UNITED STATES OF AMERICA, AS REPRESENTED BY TH |
发明人 |
BOYD, MICHAEL, R.;CARDELLINA, JOHN, H., II;SNADER, KENNETH, M.;GUSTAFON, KIRK, R.;PATTERSON, GREGORY, M., L.;MCMAHON, JAMES, B.;WEISLOW, OWEN, S.;SHOEMAKER, ROBERT, H.;PAULL, KENNETH, D. |