发明名称 |
Xanthine compounds. |
摘要 |
<p>Novel xanthine compounds represented by the following formula: <CHEM> wherein each of R<1>, R<2> and R<3> independently represents a hydrogen atom or a lower alkyl group; each of X<1> and X<2> independently represents an oxygen or sulfur atom; <CHEM> represents a single bond or a double bond; Y represents a single bond or an alkylene group, n represents 0 or 1, each of W<1> and W<2> independently represents a hydrogen atom, a lower alkyl or amino group, Z represents -CH2-, -O-, -S- or -NH-residues; provided that when Q is <CHEM> then R<1>, R<2> and R<3> are not simultaneously methyl; and physiologically acceptable salts thereof have a diuretic effect, a renal-protecting effect and/or a bronchodilatory effect. The compounds are useful as a diuretic, a renal-protecting agent and /or bronchodilator.</p> |
申请公布号 |
EP0415456(A2) |
申请公布日期 |
1991.03.06 |
申请号 |
EP19900116791 |
申请日期 |
1990.08.31 |
申请人 |
KYOWA HAKKO KOGYO CO., LTD. |
发明人 |
SUZUKI, FUMIO;SHIMADA, JUNICHI;ISHII, AKIO;OHNO, TETSUJI;KARASAWA, AKIRA;KUBO, KAZUHIRO;NONAKA, HIROMI |
分类号 |
A61K31/52;A61K31/522;A61P7/10;A61P9/08;A61P9/12;A61P13/02;A61P15/00;C07D473/06;C07D473/08;C07D473/10;C07D473/12;C07D473/20;C07D473/22;(IPC1-7):A61K31/52 |
主分类号 |
A61K31/52 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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