发明名称 |
NON-RADIOACTIVE CARRIERS AND RADIOACTIVE DIAGNOSTIC AGENT |
摘要 |
A radioactive diagnostic agent which comprises (1) the unit of a polyformyl compound having at least three formyl groups per molecule, (2) at least two units of an amino group-containing chelating compound bonded to the polyformyl compound with intervention of a methyleneimine linkage (-CH=N-) or a methyleneamine linkage (-CH2NH-) formed by the condensation between the formyl group in the polyformyl compound and the amino group in the chelating compound, optionally followed by reduction, (3) at least one unit of an amino group-containing physiologically active substance bonded to the polyformyl compound with intervention of a methyleneimine linkage or a methyleneamine linkage formed by the condensation between the formyl group in the polyformyl compound and the amino group in the physiologically active substance, optionally followed by reduction, and (4) at least two radioactive metallic elements of which each is bonded to the chelating compound through a chelating bond. |
申请公布号 |
EP0111311(B1) |
申请公布日期 |
1991.03.06 |
申请号 |
EP19830112331 |
申请日期 |
1983.12.08 |
申请人 |
NIHON-MEDI PHYSICS CO., LTD. |
发明人 |
TAKAHASHI, KEIETSU NIHON MEDI-PHYSICS CO., LTD.;UEDA, NOBUO;HAZUE, MASAAKI |
分类号 |
A61K51/00;A61K47/48;A61K51/08;A61K51/10 |
主分类号 |
A61K51/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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