| 摘要 |
The invention involves the use of absorbable or absorbable/nonabsorbable components to fabricate textile vascular grafts of all sizes and specifically for repair of the peripheral vascular system and for coronary bypass use. The bioabsorbable component of the graft fosters increased tissue ingrowth into the graft as compared to conventional 100% nonabsorbable grafts. Increased tissue ingrowth leads to greater patency through formation of a vascularized neointima and less tendency to be aneurysmal through formation of a suitable adventitia. The absorbable component can be a variety of materials, including PGA, MAXON TM , etc., whereas the nonabsorbable component (to be used as the backbone) can be new materials, e.g. NOVAFIL TM , or more conventional polymers, including polyester, polyamide or polypropylene. A knitted vascular graft, having two different absorbable fibers and a nonabsorbable fiber, can be made of the components, where one of the absorbable components is a copolymer containing glycolic acid ester linkages. |
