INDOLOBENZOQUINOLINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS ANTI-ARRYTHMIC DRUGS

摘要

Optically active compounds of formula (I): (I) in which R1 is hydrogen or alkyl; Xb and Yb are hydrogen or hydroxy; and Z is -NRaRb in which Ra and Rb are hydrogen, alkyl or hydroxyalkyl, or a cyclic amino group; and pharmaceutically acceptable salts thereof have enhanced anti-arrhythmic activity and may be prepared by a stereospecific synthesic process.