| 摘要 |
PURPOSE:To obtain an antimicrobial agent effective for material of organism, having high affinity for organisms, safety and antimicrobial action for a long period of time by supporting an antimicrobial agent such as hinokitiol, tannin, protamine or sorbic acid on hydroxyapatite. CONSTITUTION:One or more antimicrobial agents such as hinokitiol, tannin, lysozyme, allyl isothiacyanate, protamine and sorbic acid are supported on hydroxyapatite. The hydroxyapatite may be synthetic hydroxyapatite prepared from bovine bone or fish or synthetic one and has preferably about 0.02-30mum particle size. The amount of the antimicrobial agent supported on the hydroxyapatite is preferably 0.01-10% based on hydroxyapatite. The prepared objective antimicrobial compound is safely usable and <=50%, preferably about 0.1-20% of the compound is added to other materials to show sufficient antimicrobial power. |
