Process for preparing 1-, 1,5- or 2,5-substituted 1,5- or 2,5-dihydro-4H-pyrazole[3,4-d]pyrimidin-4-ones which can be used as medicaments

摘要

PCT No. PCT/DK84/00057 Sec. 371 Date Feb. 26, 1985 Sec. 102(e) Date Feb. 26, 1985 PCT Filed Jun. 19, 1984 PCT Pub. No. WO85/00368 PCT Pub. Date Jan. 31, 1985.Compounds of the formula Ia and Ib Ia Ib are prodrugs of allopurinol and have i.a. a much higher solubility in water and/or a higher lipophilicity than allopurinol, which makes such compounds useful for oral, parenteral and rectal administration to a warm-blooded animal such as a human. Such compounds will after administration be converted into allopurinol.