| 发明名称 |
DIOL METABOLITES OF 7-PHENYL-1,2,4-TRIAZOLO(2,3-C)PYRIMIDENES-5-AMINES |
| 摘要 |
A glycol of a triazolopyrimidine diuretic of formula (I) which is a metabolite and which exhibits fewer cardiotoxic side effects than the parent compound, but with no decrease in diuretic activity. The invention further provides for compositions incorporating the metabolite, and methods of its use as well as pharmaceutically acceptable salts thereof. <CHEM> |
| 申请公布号 |
ZA8909837(B) |
申请公布日期 |
1991.02.27 |
| 申请号 |
ZA19890009837 |
申请日期 |
1989.12.21 |
| 申请人 |
G.D. SEARLE & CO. |
发明人 |
EARL GEORGE BURTON;CHRISTOPHER PETER CHENGELIS;GERALD MICHAEL WALSH |
| 分类号 |
A61K31/505;A61P3/00;A61P7/10;A61P9/00;A61P9/12;A61P13/02;A61P15/00;C07D487/04 |
主分类号 |
A61K31/505 |
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