| 摘要 |
PURPOSE:To obtain an external preparation showing excellent antiinflammatory action and percutaneous absorption effect, containing a substance prepared by culturing a bacterium belonging to the genus Bacillus in Zizania latifolia O.Stapf or a relative thereof as a medium. CONSTITUTION:Zizania latifolia O.Stapf, a gramineous plant or a relative thereof is treated with a bacterium belonging to the genus Bacillus and the bacterium is cultured and a substance such as a single substance of live bacterium, an enzyme, a fraction prepared after removal of the bacterium from the culture mixture or a fraction prepared after removal of the enzyme from the culture mixture is prepared to give an external preparation containing Zizania latifolia O.Stapf as an active ingredient. B. subtilis, B. cereus, B. megaterium, B. polymyxa or B. amyloliquefaciens is used as the bacterium belonging to the genus Bacillus. Protease, polygalacturonase, pectinase, beta-1,3-glucanase, lipase or amylase may be cited as the enzyme. |
