发明名称 COUPLING OF AN ANTI-TUMOR TO AN ANTIBODY USING GLUTARALDEHYDE PREACTIVATED ANTI-TUMOR AGENT
摘要 <p>The present invention relates to antitumor compounds of formula (I) wherein M is selected from the group consisting of an hydrogen atom, a peptide residue, and a protein residue linked to the carbon atom via the amino residue of ε-lysine present therein which can be an antibody used to target the anti-tumor agent to the malignant cells, and R can be an antitumor agent such as daunorubicin, doxorubicin or an epirubicin derivative.</p>
申请公布号 WO1991001757(A1) 申请公布日期 1991.02.21
申请号 CA1990000251 申请日期 1990.08.09
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