BONDED PHASE OF SILICA FOR SOLID PHASE EXTRACTION

摘要

For solid-phase clean-up of urine samples, e.g. in the analysis of cannabinoids, a novel solid-phase bonded silica product has the formula …… is the backbone of a silica gel or controlled pore glass;… X is -O-, -S-, -O-CH2-CHOH-CH2-O- or -O-CH2-CHOH-CH2-S-;… n is 2, 3, 4 or 5;… p is 0 or 1;… each R and R<1> (if present) are independently selected from H, C1-3 alkyl and -(CH2)m-COOR<3> wherein R<3> is C1-4 alkyl and m is 1, 2, 3 or 4; and… R<2> is C1-4 alkyl.